Hyperemesis gravidarum, or extreme nausea and vomiting during pregnancy, can affect up to two percent of pregnancies. Risk factors for hyperemesis include a history of having it in a prior pregnancy or a family history of hyperemesis, carrying twins or triplets, or carrying a female fetus. There is actually some data that shows that women with hyperemesis have a lower miscarriage rate, which is thought to be due to the robust placenta and elevated pregnancy hormone levels.

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